產品詳情
簡單介紹：
Anti-phospho-ATF2 (Ser490/498)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-ATF2 (Ser490/498)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-ATF2 (Ser490/498)
Cat. Number:
Anti-phospho-ATF2 (Ser490/498)抗體XY-1648R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ATF2 is a member Anti-phospho-ATF2 (Ser490/498)抗體of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and Anti-phospho-ATF2 (Ser490/498)抗體p38 MAP kinase. ATF2 is abundantly expressed in brain.
Also known as:
ATF2 (phospho S490); Anti-phospho-ATF2 (Ser490/498)抗體p-ATF2 (phospho S490); ATF2 (phospho S490 + S498); p-ATF2 (phospho S490 + S498); CREB 2; HB 16;Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive.
Specificity:
●
Rabbit Polyclonal IgG, Anti-phospho-ATF2 (Ser490/498)抗體affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human ATF2 around the phosphorylation site of Ser490/498.
●
Predicted Molecular Weight: 45kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
xy-13823R phospho-CEBPE (Thr74)磷酸化轉錄調節因子C/EBPε抗體
xy-13826R CEECAM1腦血管內皮細胞粘附分子1抗體
xy-13804R C1QL4補體C1QL4鏈多肽抗體
xy-13781R C19orf219號染色體開放閱讀框2抗體
xy-13807R CCDC62卷曲螺旋結構域蛋白62抗體
xy-13808R CCDC64卷曲螺旋結構域蛋白64抗體
xy-13811R CCDC72卷曲螺旋結構域蛋白72抗體
xy-13812R CCDC73卷曲螺旋結構域蛋白73抗體
xy-13813R CCDC74B卷曲螺旋結構域蛋白74B抗體
xy-13782R C19orf2519號染色體開放閱讀框25抗體
xy-13783R C19orf4219號染色體開放閱讀框42抗體
xy-13784R C19orf4419號染色體開放閱讀框44抗體
xy-13785R C19orf4819號染色體開放閱讀框48抗體
xy-13786R C19orf5019號染色體開放閱讀框50抗體
xy-13787R C19orf5119號染色體開放閱讀框51抗體
xy-13788R C19orf5219號染色體開放閱讀框52抗體
xy-13789R C19orf5519號染色體開放閱讀框55抗體
xy-13790R C19orf5619號染色體開放閱讀框56抗體
xy-13791R C19orf5719號染色體開放閱讀框57抗體
xy-13792R C19orf6119號染色體開放閱讀框61抗體
xy-13798R C19orf7719號染色體開放閱讀框77抗體
xy-13800R C1D核DNA結合蛋白C1D抗體
xy-13757R C1orf1581號染色體開放閱讀框58抗體
xy-13758R C21orf6621號染色體開放閱讀框66抗體
xy-13759R CDC42EP3CDC42效應蛋白3抗體
xy-15268R C7orf 437號染色體開放閱讀框43抗體
xy-10351R phospho-c-ABL (Tyr115)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10356R phospho-c-Abl (Thr754 + Thr735) 磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10355R phospho-c-ABL (Tyr245)磷酸化非受體酪氨酸激酶c-Abl抗體
