国产精品精品久久久久久,成熟女人特级毛片www免费,日韩综合网站

產(chǎn)品展示

產(chǎn)品詳情

查看大圖

產(chǎn)品名稱(chēng)：重組人白細(xì)胞介素-33蛋白
產(chǎn)品型號(hào)：rHuIL-33
產(chǎn)品廠商：KALANG
產(chǎn)品文檔：

你添加了1件商品查看購(gòu)物車(chē)

簡(jiǎn)單介紹：

重組人白細(xì)胞介素-33蛋白與其它公司提供的重組蛋白不同，rHuIL-33蛋白產(chǎn)品為采用CFS的無(wú)細(xì)胞麥胚蛋白合成系統(tǒng)表達(dá)出來(lái)的重組蛋白，可表達(dá)出對(duì)細(xì)胞有毒性、易被蛋白酶降解的蛋白；并獲得具有良好的可溶性，并有翻譯后修飾、從而部分具有功能的蛋白.同時(shí)獨(dú)有的全自動(dòng)蛋白純化技術(shù)則簡(jiǎn)便高效，將蛋白純化過(guò)程中對(duì)蛋白的損傷降低到*小程度.重組人白細(xì)胞介素-33蛋白（全長(zhǎng)序列）產(chǎn)品可用于Western Blot驗(yàn)證、抗體制備、蛋白檢測(cè)、ELISA等試驗(yàn)中.

詳情介紹：

重組人白細(xì)胞介素-33蛋白

Synonyms IL-1F11, NF-HEV, DVS 27

Species Human

Accession O95760

GeneID 90865

Source Escherichia coli.

Molecular Weight 重組人白細(xì)胞介素-33蛋白Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.

Quantity 2μg/10μg/1000μg

AA Sequence SITGISPITE YLASLSTYND QSITFALEDE SYEIYVEDLK KDEKKDKVLL SYYESQHPSN ESGDGVDGKM LMVTLSPTKD FWLHANNKEH SVELHKCEKP LPDQAFFVLH NMHSNCVSFE CKTDPGVFIG VKDNHLALIK VDSSENLCTE NILFKLSET

Purity > 97 % by SDS-PAGE and HPLC analyses.

Biological Activity 重組人白細(xì)胞介素-33蛋白Fully biologically active when compared to standard. The ED₅₀ as determined by a cell proliferation assay using murine D10S cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 10⁷ IU/mg.

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, 150 mM NaCl, 1mM EDTA, pH7.4.

Endotoxin Less than 1 EU/μg of rHuIL-33 as determined by LAL method.

Reconstitution 重組人白細(xì)胞介素-33蛋白We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Storage This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

重組人白細(xì)胞介素-33蛋白

SDS-PAGE

Reference 1. Liew FY, Pitman NI, McInnes IB. 2010. Nat Rev Immunol, 10: 103-10.
2. Miller AM, Xu D, Asquith DL, et al. 2008. J Exp Med, 205: 339-46.
3. Bourgeois E, Van LP, Samson M, et al. 2009. Eur J Immunol, 39: 1046-55.
4. Zhiguang X, Wei C, Steven R, et al. 2010. Immunol Lett, 131: 159-65.
5. Turnquist HR, Zhao Z, Rosborough BR, et al. 2011. J Immunol, 187: 4598-610.

Background IL-33, encoded by IL-33 gene located on the Chr.9 in humans, is a 30 kDa proinflammatory protein belonging to the IL-1 superfamily and it shares less than 20 % a.a. sequence identity with other members. IL-33 secreted by high endothelial venules at high levels, which is found in tonsils, peyer patches and mesenteric lymph nodes, but not in placenta. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1α or IL1β stimulation. It elicits its biological effects by interacting with IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 mature protein has 52-58 % a.a. sequence identity with mouse and rat IL-33.

標(biāo)題：

內(nèi)容：

聯(lián)系人：

聯(lián)系電話：

Email：

公司名稱(chēng)：

聯(lián)系地址：

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發(fā)送信息!

2.如有必要,請(qǐng)您留下您的詳細(xì)聯(lián)系方式!

滬公網(wǎng)安備 31011702004399號(hào)

Synonyms	IL-1F11, NF-HEV, DVS 27
Species	Human
Accession	O95760
GeneID	90865
Source	Escherichia coli.
Molecular Weight	重組人白細(xì)胞介素-33蛋白Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.
Quantity	2μg/10μg/1000μg
AA Sequence	SITGISPITE YLASLSTYND QSITFALEDE SYEIYVEDLK KDEKKDKVLL SYYESQHPSN ESGDGVDGKM LMVTLSPTKD FWLHANNKEH SVELHKCEKP LPDQAFFVLH NMHSNCVSFE CKTDPGVFIG VKDNHLALIK VDSSENLCTE NILFKLSET
Purity	> 97 % by SDS-PAGE and HPLC analyses.
Biological Activity	重組人白細(xì)胞介素-33蛋白Fully biologically active when compared to standard. The ED₅₀ as determined by a cell proliferation assay using murine D10S cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 10⁷ IU/mg.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, 150 mM NaCl, 1mM EDTA, pH7.4.
Endotoxin	Less than 1 EU/μg of rHuIL-33 as determined by LAL method.
Reconstitution	重組人白細(xì)胞介素-33蛋白We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage	This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
重組人白細(xì)胞介素-33蛋白
SDS-PAGE
Reference	1. Liew FY, Pitman NI, McInnes IB. 2010. Nat Rev Immunol, 10: 103-10. 2. Miller AM, Xu D, Asquith DL, et al. 2008. J Exp Med, 205: 339-46. 3. Bourgeois E, Van LP, Samson M, et al. 2009. Eur J Immunol, 39: 1046-55. 4. Zhiguang X, Wei C, Steven R, et al. 2010. Immunol Lett, 131: 159-65. 5. Turnquist HR, Zhao Z, Rosborough BR, et al. 2011. J Immunol, 187: 4598-610.
Background	IL-33, encoded by IL-33 gene located on the Chr.9 in humans, is a 30 kDa proinflammatory protein belonging to the IL-1 superfamily and it shares less than 20 % a.a. sequence identity with other members. IL-33 secreted by high endothelial venules at high levels, which is found in tonsils, peyer patches and mesenteric lymph nodes, but not in placenta. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1α or IL1β stimulation. It elicits its biological effects by interacting with IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 mature protein has 52-58 % a.a. sequence identity with mouse and rat IL-33.

產(chǎn)品名稱(chēng)：重組人白細(xì)胞介素-33蛋白